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Deep reinforcement learning (DRL) has demonstrated significant potential in various applications, including gaming AI, robotics, and system scheduling. DRL algorithms produce, sample, and learn from training data online through a trial-and-error process, demanding considerable time and computational resources. To address this, distributed DRL algorithms and paradigms have been developed to expedite training using extensive resources. Through carefully designed experiments, we are the first to observe that strategically increasing the actor-environment interactions by spawning more concurrent actors at certain training rounds within ephemeral time frames can significantly enhance training efficiency. Yet, current distributed DRL solutions, which are predominantly server-based (or serverful), fail to capitalize on these opportunities due to their long startup times, limited adaptability, and cumbersome scalability. This paper proposesNitro, a generic training engine for distributed DRL algorithms that enforces timely and effective boosting with concurrent actors instantaneously spawned by serverless computing. With serverless functions,Nitroadjusts data sampling strategies dynamically according to the DRL training demands.Nitroseizes the opportunity of real-time boosting by accurately and swiftly detecting an empirical metric. To achieve cost efficiency, we design a heuristic actor scaling algorithm to guideNitrofor cost-aware boosting budget allocation. We integrateNitrowith state-of-the-art DRL algorithms and frameworks and evaluate them on AWS EC2 and Lambda. Experiments with Mujoco and Atari benchmarks show thatNitroimproves the final rewards (i.e., training quality) by up to 6Ă— and reduces training costs by up to 42%.more » « lessFree, publicly-accessible full text available September 1, 2026
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Biocompatible polymers have emerged as essential materials in medical 3D printing, enabling the fabrication of scaffolds, tissue constructs, drug delivery systems, and biosensors for applications in and on the human body. This review aims to provide a comprehensive overview of the current state of 3D-printable biocompatible polymers and their composites, with an emphasis on their processing methods, properties, and biomedical uses. The scope of this work includes both natural and synthetic biocompatible polymers, polymer–nanocomposite systems, and bioinks that do not require photo initiators. The relevant literature was critically examined to classify materials by type, evaluate their compatibility with major 3D printing techniques such as stereolithography, selective laser sintering, and fused deposition modeling, and assess their performance in various medical applications. Key findings highlight that reinforced polymer composites, tailored surface chemistries, and hybrid printing strategies significantly expand the range of functional, customizable, and affordable biomedical devices. This review concludes by discussing present-day applications and emerging trends, underscoring that 3D-printable biocompatible polymers are rapidly transitioning from research to clinical practice, offering transformative potential for patient-specific healthcare solutions.more » « lessFree, publicly-accessible full text available August 1, 2026
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